MOLECULAR PARTNERS - Group Leader / Translational Lead M/F

Molecular Partners — Zurich-Schlieren
11.09.2019Executive po­si­tion100%

Founded in 2004 by a group of PhD students as a spin-off from the University of Zurich, Molecular Partners AG is a thriving and steadily growing clinical stage biotech company located in Zurich-Schlieren (Switzerland) with 140 highly qualified employees.

In order to advance modern medicine and significantly improve the management of serious diseases, we have developed and successfully established a powerful new class of potent, specific and versatile small protein therapies, called DARPin® therapeutics.

The continuous development of a broad portfolio of therapeutic product candidates in oncology and ophthalmology based on the company’s proprietary DARPin® platform allowed a successful listing of the company on the SIX Swiss Exchange (ticker: MOLN). Next to our own pipeline of drug candidates we have entered into collaborations with leading international pharmaceutical companies, including Allergan, Amgen, Roche and Janssen Pharmaceuticals.

The highly dedicated, multi-disciplined team at MP is committed to developing breakthrough medicines for serious diseases.

MOLECULAR PARTNERS - Group Leader / Translational Lead M/F

As an addition to the Translational Science team we are looking for a motivated Group Leader/Translational Lead. In this challenging role you will be responsible for the following tasks:

  • Lead an ex vivo group and accountable for delivering translational data package on biomarker validation and MoA understanding using IHC, FACS, gene expression analaysis and tissue culture on specimens from human and other pharmacology/tox-relevant species
  • Develop and implement translational plans, including PK/PD data package and biomarker plan, to support transit of preclinical assets into early clinical development in oncology indications
  • Contribute to translational science strategy development for target engagement, pharmacodynamics, mechanism of action, and patient selection, in line with clinical development strategy
  • Manage the implementation of translational/ biomarker plan by effectively engaging scientific/technical experts in research and development colleagues including bioanalytical team
  • Effectively interface with the project team to obtain appropriate resources to deliver on biomarker goals
  • Develop and implement exploratory analysis plans for clinical biomarker data
  • Collaborate with external partners and CROs conducting studies to ensure operational success

Molecular Partners
Frau Barbara Weber
Wagistrasse 14
8952 Schlieren
+41 44 755 57 65

3 jobs — Schlieren

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