PostDoc in Neuropsychiatry and Biomarkers

Our research focuses on the early stages of cognitive decline, delirium and persisting neuropsychiatric syndromes in late adulthood and old age. Our main goals are to 1) better understand the pathophysiological mechanisms associated with neurocognitive and neuropsychiatric disorders, and their relevance for the clinical manifestations and the course of disease, 2) identify and validate biomarkers for prediction, early detection and differential diagnosis of cognitive impairment and related neuropsychiatric symptoms and 3) identify risk factors and protective factors of cerebral aging to assess risk and develop approaches for prevention and treatment.

The current projects focus on the integration of multi-omics data with clinical data from an existing cohort as well as a multi-centric cohort with ongoing recruitment and follow-up. The project includes several collaborations with local and international groups and labs.

PostDoc in Neuropsychiatry and Biomarkers

The successful candidate will take a leading role in statistical and methodological approaches as well as substantially contribute to the scientific output of the group by publishing in peer-reviewed journals and by presenting results at international conferences. Additionally, the candidate will supervise graduate and master students and will be trained in study related tasks (basic lab work, help with MRI scanning, biobanking).

• PhD and/or expertise in data science, bioinformatics, biostatistics, neurosciences, and pathophysiology
• Advanced knowledge with statistical data modelling (single-omics and multi-omic data integration, multivariate statistics including PCA, linear mixed effects models, etc.) is necessary
• Excellent scientific track record, including at least one publication as first author in a good quality, peer reviewed international journal
• Experience in the field of Alzheimer's disease and/or neurodegenerative diseases and in biomarker discovery is also highly desired
• Commitment and capacity to work effectively in a multidisciplinary team and multiple local and international collaborations
• Interest on clinical research
• Excellent communication skills in English (spoken and written); German desirable

• Possibility to combine basic research and applied clinical research
• Possibility to work on interdisciplinary and highly collaborative projects in a very motivated team
• Joining an ongoing and very successful project with already available large data-sets to be used straight away
• Home-office on single days possible
• Very good salary, according to local university regulations and standards in Switzerland

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