PhD position in the Microglia Biology
Date de publication :
15 mai 2025Taux d'activité :
100%- Lieu de travail :Lausanne
Résumé de l'emploi
L'UNIL, institution de recherche et d'enseignement, recherche un doctorant.
Tâches
- Étudier les mécanismes moléculaires des microglies dans les maladies cérébrales.
- Utiliser des techniques telles que la microscopie et le séquençage scRNA.
- Analyser l'impact des facteurs génétiques sur la fonction des microglies.
Compétences
- Diplôme de Master en sciences de la vie et expérience en biologie moléculaire.
- Fluente en anglais, compétences en microscopie.
- Intérêt marqué pour la neurobiologie.
Est-ce utile ?
Introduction
UNIL is a leading international teaching and research institution, with over 5,000 employees and 17,000 students split between its Dorigny campus, CHUV and Epalinges. As an employer, UNIL encourages excellence, individual recognition and responsibility.
Presentation
One funded PhD position is available in the Microglia Biology Lab, headed by Prof. Rosa Chiara Paolicelli at the Department of Biomedical Sciences, University of Lausanne, to study the molecular and cellular mechanisms underlying microglial contribution to brain diseases.
Job information
Expected start date in position : 01.07.2025
Contract length : 1 year, renewable
Activity rate : Full time position
Workplace : Department of Biomedical Sciences - Prof. Rosa Chiara Paolicelli
Your responsibilities
Microglia, the resident immune cells of the central nervous system, are important for proper brain development and for maintaining neural homeostasis throughout life. Growing evidence also implicates them as key contributors to various brain disorders. However, the underlying mechanisms are highly heterogeneous and still poorly defined.
The goal of the project is to study the role of genetic factors and metabolic regulation as modulators of microglial function and microglia-mediated synapse loss, by using in vitro, ex vivo and in vivo approaches
Your qualifications
A variety of techniques will be used, including confocal microscopy, scRNA-sequencing and spatial transcriptomics, and behavioral characterization of mouse models.
Previous experience in molecular biology, microscopy and/or animal handling is highly appreciated.
Candidates are required to be fluent in English (written and spoken), and to have a Master's degree in life science or equivalent, and a strong interest in neurobiology.
What the position offers you
The University of Lausanne is a higher teaching and research institution composed of seven faculties where approximately 15,000 students and nearly 5,000 collaborators, professors, and researchers work and study. Ideally situated along the lake of Geneva, near Lausanne's city center, its campus brings together over 120 nationalities.
Contact for further information
Rosa Paolicelli
E-Mail schreiben
Your application
Highly motivated candidates are encouraged to apply by sending their CV, along with a motivation letter and two reference letters, to E-Mail schreiben
Deadline : 02.06.2025
Please, send your full application in Word or PDF.
Only applications through this website will be taken into account.
We thank you for your understanding.
Additional information
UNIL is committed to:
• equality, diversity and inclusion within its community;
• ensuring an open and respectful environment that is conducive to personal development;
• offering working conditions that facilitate work-life balance;
• supporting early career researchers.
unil.ch/equality
unil.ch/families
unil.ch/graduatecampus
