Master-student internship in cellular and molecular biology – Neuromuscular in vitro models (12 months)

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The Position

Job Summary
Internship position in an industry-leading interdisciplinary lab to work on the development and characterization of cellular models of the neuromuscular junction

The Position
We are looking for a highly motivated intern (current or recently graduated Master student) to join the Neurogenomics Section in Neuroscience and Rare Disease (NRD) at Roche. The project is focused on the establishment and characterization of cellular models of the neuromuscular junction and will give you the opportunity to gain experience in iPSC work, cellular engineering and in vitro differentiation, gene expression analysis, high-throughput assay development, immunohistochemistry, confocal microscopy, and live imaging.
You will benefit of the supervision of experienced scientists and of a highly collaborative Neuroscience department. You will have the opportunity to experience a world-leading industry setting and contribute to changing the lives of patients with devastating brain disorders.

As an Intern your responsibilities will be:
- Culture and characterize iPSC-derived muscle and neuronal cells
- Establish differentiation protocols for these cells
- Evaluate cells in biochemical and functional assays
- Record experiments and data according to industry standards
- Analyze data and present results at lab meetings
- Work as part of a multi-disciplinary team

You are / have:

• Biology, biotechnology, biochemistry, neuroscience or molecular biology student, enrolled in a Master’s degree program or within a year from completion at the start of the internship
• Motivated to learn new techniques to explore the biology of neurodegenerative disorders
• Practical experience with mammalian cell culture. Previous experience with cultivation and differentiation of iPSC-derived cells will be considered a plus
• Basic experience in molecular and biochemical assays (qRT-PCR / Westernblot / ELISA)
• Experience in microscopy will be considered a plus
• A self-motivated and independent thinker with excellent communication skills, attention to detail, and the desire to work in a fast-paced environment
• Fluent in English (writing and speaking)

The position is based in Basel, Switzerland. Earliest possible starting date is 01.10.2024.

Applications need to include both a CV and a motivation letter.

Due to regulations non-EU/EFTA citizens must provide a certificate from the university stating that an internship is mandatory as part of the application documents.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.