Die Universität Bern und das Universitätsspital Bern suchen Unterstützung. Eine spannende Chance in einem innovativen Team!
Aufgaben
Identifizierung der mathematischen Strukturen für PK/PD-Modelle.
Literaturrecherche zu Physiologie und Wirkmechanismen neuer Medikamente.
Simulation und Parameteridentifikation mit vorhandenen Daten.
Fähigkeiten
Masterstudent:in in Pharmazie, biomedizinischer Technik oder ähnlichem.
Erfahrung in PK/PD-Modellen für Medikamente oder Biomarker.
Kenntnisse in Programmierung (Matlab, Python oder ähnlich).
Ist das hilfreich?
University of Bern and University Hospital Bern, Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism (UDEM) Start of employment: By arrangement Employment: limited term of three years - after three years, depending on further funding. PrecisionLab, led by Prof. Jose Garcia-Tirado, aims to develop new technology for managing diabetes and metabolic disorders through novel digital interventions such as advanced decision-support tools and automated insulin delivery.
Job purpose and responsibilities
You work primarily on identifying the mathematical structure and parameters of a compartmental model describing the pharmacokinetic (PK)/pharmacodynamic (PD) of novel incretin medications used for glucose control and body weight reduction in people with type 2 diabetes. Specifically:
Review the literature to understand the physiology mechanisms of action of these medications
Propose different mathematical structures describing the PK of a selected medication candidate and test them in simulation
Carry out the identification of the model parameter distributions using data from the literature
Requirements
A Must:
Master student in pharmacy, biomedical engineering, or a close field
Previous experience in identifying PK/PD models for drugs or biomarkers
Previous experience in computer programming (Matlab, Python, or similar)
We offer
We provide excellent scientific expertise in a dynamic environment and support a career focusing on translational research
A workplace in Bern, Switzerland's capital, known for its high quality of life and surrounded by beautiful nature, perfect for hiking, biking, swimming, and winter sports
Application and contact
For subject-specific questions and information about the position, please contact E-Mail schreiben.
