Postdoctoral research position, immunogenic cell death in acute leukemia

Postdoctoral research position, immunogenic cell death in acute leukemia

Located in the Campus Lengg of the University of Zurich, and soon in the newly built research tower of the Kinderspital, we apply and develop state-of-the-art technologies including single cell analytics, CRISPR-based genome editing, machine learning algorithms, high content data analysis and ex-vivo / in vivo PDX models. We are embedded in a strong precision oncology network at UZH with strong ties with the ETH Zurich and are centrally involved in international clinical trials for childhood leukemia providing a relevant context to our research program.The employment is limited to 2 years with the option of extension.

Postdoctoral research position, immunogenic cell death in acute leukemia

• You explore the cell biology of various cell death pathways (apoptosis, pyroptosis, necroptosis, ferroptosis) and their potential to eradicate resistant disease in the context of acute leukemia of childhood.
• You dissect the relationship between intrinsic and extrinsic signaling programs using a representative xenograft bank of primary leukemia.
• You Investigate the immunogenic aspect of programmed cell death instances.
• You work in an agile and collaborative lab environment and contribute to scientific discovery.
• You will apply state-of-the-art laboratory methodologies.
• You are receptive for encouragement and support for innovative and actionable ideas.
• You have the opportunity to work in a multidisciplinary environment with molecular and cellular biologists, clinicians, computer scientists, and international collaborators.

• You have a strong appetite for scientific discovery and a strong interest in disease modeling, cell death research, and biomedical computing.
• You have a strong experimental track record.
• You are motivated to work together with a focused task force and to guide master and PhD students.
• You hold an MD-PhD or PhD in biological or biomedical sciences or equivalent.
• You have strong analytical and problem-solving skills and are comfortable with planning, prioritizing, conducting, analyzing and communicating research in a variety of contexts.
• You communicate actively with collaborators, colleagues and team members with proficiency in English.

We offer varied and interesting work in an inspiring and socially relevant environment.
Diversity and inclusion are important to us.

PD Dr. Beat Bornhauser, Head of research Dept. of Pediatric OncologyApplication