Postdoctoral Researcher in Next-Generation T-Cell Engineering

Introduction

UNIL is a leading international teaching and research institution, with over 5,000 employees and 17,000 students split between its Dorigny campus, CHUV and Epalinges. As an employer, UNIL encourages excellence, individual recognition and responsibility.

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Presentation

The T-cell Engineering Laboratory led by Dr Melita Irving in the Department of Fundamental Oncology at the University of Lausanne invites applications for a Postdoctoral Researcher in Next-Generation T-Cell Engineering. Our team develops innovative CAR- and TCR-engineered T-cell therapies for cancer, combining cellular immunology, genetic engineering and preclinical research. We welcome candidates with strong immunology expertise, including complementary research backgrounds, who are enthusiastic about advancing cancer immunotherapy.

Job information

Expected start date in position : 01.12.2026

Contract length : 1 year

Employment rate : 100%

Workplace : Epalinges, Lausanne

Your responsibilities

• Develop and characterise next-generation CAR- and TCR-engineered T cells, using molecular and cellular immunology approaches.


• Design and perform in vitro experiments, including multiparameter flow cytometry, cytokine production and cytotoxicity assays, using T-cell/tumour-cell cocultures, tumour spheroids and patient-derived tumour material.


• Participate in and perform in vivo preclinical tumour studies, following completion of the required training and authorisations.


• Independently lead a defined research project, including experimental planning, documentation, data analysis, troubleshooting and communication of results, while contributing to manuscripts and collaborating closely with laboratory members and external collaborators.


• Contribute to general laboratory maintenance, organisation and shared responsibilities, as coordinated by the laboratory manager.


• Work in a cordial, respectful, diligent and rigorous manner.

Your qualifications

• PhD in immunology or a related biomedical discipline; applicants with complementary immunology backgrounds are encouraged.


• Strong practical immunology skills, including cell culture, flow cytometry, molecular biology and/or functional immune assays.


• Experience in T-cell culture, genetic modification or CAR/TCR engineering is advantageous.


• Willingness to undertake in vivo experimental studies is essential. Previous experience with animal models and LTK1 certification are advantageous but not required. The successful candidate will be expected to complete the necessary training and obtain the relevant authorisations.


• Scientific curiosity, rigour, independence, teamwork and strong written and spoken English.

What the position offers you

Join a dynamic, international and collaborative research team dedicated to developing innovative T-cell therapies for cancer. We offer a stimulating scientific environment with opportunities to contribute to cutting-edge research in CAR and TCR engineering, develop expertise in advanced in vitro and in vivo preclinical models, and work alongside researchers with complementary expertise. The position provides opportunities for scientific independence, professional development and collaboration within a supportive academic environment.

Contact for further information

Dr Melita Irving (email: E-Mail schreiben)

Tél : +41216925961

Your application

Application deadline : 09.10.2026

Please include a motivation letter, full curriculum vitae with publication list, and contact details for two referees.
Only applications through this website will be taken into account.

We thank you for your understanding.

Additional information

UNIL is committed to:
•    equality, diversity and inclusion within its community;
•    ensuring an open and respectful environment that is conducive to personal development;
•    offering working conditions that facilitate work-life balance;
•    supporting early career researchers.

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